Bioengineering Gene Expression


A recent article at Sciencedaily called Bioengineers Devise ‘Dimmer Swith’ To Regulate Gene Expression In Mammal Cells discusses new technology being developed that combined a targeted DNA repressor protein, and a custom-designed RNAi strand. The repressor is thought to prevent most transcription, but in the event not all genes are repressed, the RNAi is thought to hunt out those transcripts, and destroy them.

Another chemical called Isopropyl-รข-thiogalactopyranoside acts as a “dimmer” that can block the repressor protein. Thus by altering the amount of this chemical, repressor and RNAi, they can regulate a gene’s expression. Cool.

Play in the Mud. Fight Depression.


Maybe its not that simple, but exposure to probiotic bacteria commonly found in soil have been linked to the brain chemical, serotonin.

  • Cancer patients increased their qualities of life with exposure to Mycobacterium vaccae
  • M. vaccae activated a group of neurons to produce more serotonin mitigating depression

Full article at Getting Dirty May Lift Your Mood.

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